Feb. 28: Edward Owusu-Ansah presents on the Effect of Mitochondrial Dysfunction on Aging in Fruit Flies

The Columbia Aging Center invites you to join us on Tuesday, February 28th at 1 pm in ARB Room 440, 722 West 168th Street for this talk by Columbia Aging Center Faculty Research Fellow Edward Owusu-Ansah.

Your RSVP is requested, please email Caitlin Hawke: ColumbiaAgingCenter@cumc.columbia.edu.

This talk “The Effect of Mitochondrial Dysfunction on Aging in Drosophila”is part of our ongoing "BIOLOGIES? OF AGING" series in which our lecturers explore various biological "hallmarks" of aging, employing a variety of models from budding yeast (Saccharomyces cerevisiae) to fruit flies (Drosophila melanogaster) and worms (Caenorhabditis elegans) to vertebrates. Topics have included genetics, epigenetics, stem cells, protein homeostasis and autophagy, metabolic regulation, mitochondria, and endocrine regulation.

Abstract: The progressive deterioration of mitochondrial function is a prominent feature of aging. Accordingly, strategies to enhance or preserve mitochondrial function with age have been proposed as viable approaches for improving health and longevity. Mitochondrial Complex I is the first and largest complex of the oxidative phosphorylation system, which is involved in generating energy in the form of ATP in the mitochondrion ( the powerhouse of the cell). We will describe the approaches we are using to identify ways to improve or restore mitochondrial function with age in Drosophila.